Version 25.09.2018

International Symposium

Mechanobiology:
Measuring and Modelling Cell Migration

 

RWTH Aachen University

September 27/28, 2018

Mechanobiology: Measuring and Modelling Cell Migration 2018

Thursday, September 27th

 

12:00-13:00

Registration

MOCA, Institute of Molecular and Cellular Anatomy, Medical Faculty

Wendlingweg 2

RWTH Aachen University

D-52057 Aachen

 

12:00-13:00

Snack

 

13:00-13:15

Welcome (Coordinator)

 


Part 1: Cell contraction and invasion

Chair: Galiya Sakaeva / Co-Chair: Rutuja Patwardhan

 

13:15-14:00

Keynote lecture 1

Bill BEMENT Abstract K1

The cell cortex as an excitable medium

14:00-14:07

Flash talks 1-4

Gailya Sakaeva Abstract 01

Polarized epithelial cell migration depends on rear end stress fibre tension

14:07-14:14

Anne Pora Abstract 02

Focal adhesion-hemidesmosome crosstalk in migrating keratinocytes

14:14-14:21

Rutuja Patwardhan Abstract 03

EGF triggers Rho excitability in migrating keratinocytes

14:21-14:28

Victor Juma Abstract 04

Parameter identification for Rho-myosin model

 

14:30-15:00

The mentor's lecture

Leif DEHMELT Abstract M1

Self-organization of cell contraction dynamics

 

15:00-17:00

Poster session and coffee break

 

17:00-17:45

Keynote lecture 2

Julie PLASTINO Abstract K2

Forces drive basement membrane invasion in Caenorhabditis elegans

17:45-17:52

Flash talks 5-10

Jacopo di Russo Abstract 05

Collective cell migration: intercellular forces coordination by integrin α5β1

17:52-17:59

Aljona Gaiko-Shcherbak Abstract 06

The basement membrane: A mechanical cell invasion barrier in breast cancer

17:59-18:06

Volker Buck Abstract 07

In vitro models for studying endometrial receptivity – characterization of human biopsies in a new test system

18:06-18:13

Andreas Ludwig / Aaron Babendreyer Abstract 08

Regulation of fractalkine-induced monocytic cell recruitment by endothelial shear stress

18:13-18:20

Aldo Leal-Egana Abstract 09

Novel strategy to determine cancer cell heterogeneity in

vitro: assaying the relation force/speed/morphology

with micro-featured scaffolds

18:20-18:27

Jannis Körner Abstract 10

β1 subunit stabilises sodium channel Nav1.7 against mechanical stress

 

18:30-19:15

Keynote lecture 3

Jacky GOETZ, Sébastien HARLEPP Abstract K3

Biomechanical regulation of tumor metastasis

 

19:30-19:45

Transfer by bus

 

 

19:45-23:30

Conference dinner

Drehturm Aachen

Belvedereallee 5, 52070 Aachen

 

Friday, September 28th

 

Part 2: Cell mechanics as a basis for biomedical engineering

Chair: Rudolf Merkel / Co-Chair: Rupert Ecker

 

09:00-09:30

The mentor's lecture

Michael KOZLOV Abstract M2

Modelling membrane super-structures formed by caveolae

09:30-09:37

Flash talks 11-14

Roger Sauer Abstract 11

Advanced continuum modelling of lipid bilayer membranes

09:37-09:44

Davide Cusseddu Abstract 12

A coupled bulk-surface model for cell polarisation

09:44-09:51

Nadieh Kuijpers Abstract 13

Dynamic interaction of cytoskeletal filaments in migrating keratinocytes

09:51-09:58

Dmytro Kotsur Abstract 14

Automatic segmentation and tracking of keratin filaments in living cells

 

10:00-10:45

Keynote lecture 4

Núria GAVARA Abstract K4

The cytoskeleton, by the numbers

 

10:45-11:15

Coffee break and group photo

 

11:15-11:22

Flash talks 15-20

Saransh Vora Abstract 15

A computational framework for simulating the dynamics of keratin filament networks

11:22-11:29

Eduard Campillo-Funollet Abstract 16

A Bayesian approach to parameter identification: keratin dynamics and traction force microscopy

11:29-11:36

Clara Abaurrea Velasco Abstract 17

Active composite agents: a minimal model for motile cells

11:36-11:43

Nikos Fatsis-Kavalopoulos Abstract 18

Precise microfluidic clustering of multiple cell types for quantifying paracrine effects in cancer cells

11:43-11:50

Rupert Ecker Abstract 19

TissueFAXS Cytometry – A Tool for Precision Medicine: Automated Analysis of Single Cells and the Cellular Microenvironment

11:50-11:57

Laura Bornes Abstract 20

Keratinocytes migrate individually in a collectively migrating sheet during wound closure in vivo

 

12:00-12:30

The mentor's lecture

Stefan JOCKENHÖVEL Abstract M4

Biohybrid implant development – The role of mechanobiological stimuli

 

12:30-12:45

Closing of the meeting

Coordinators

 

12:45-14:00

Farewell snack